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The present study aimed to evaluate the effects of trimetazidine, alone or in combination with probiotics, on inflammation, oxidative stress, and ferroptosis-related pathways in 5-FUinduced intestinal mucositis in mice, with particular focus on the Nrf2/GPx4/SLC7A11 antioxidant axis

The two main changes to the brain are: 1

This is consistent with past studies revealing the antioxidant properties of GSH [55,56,57]

In particular, the expression of the insulin receptor protein, which regulates energy metabolism, has been positively correlated with mammalian longevity (Ma S