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The spleen, which is located in the upper abdomen, makes antibodies and removes old and damaged red blood cells (4)

Heme oxygenase modulates oxidant-signaled airway smooth muscle contractility: role of bilirubin

Within neurons, excess Fe + undergoes Fenton or HaberWeiss reactions, generating hydroxyl radicals that attack DNA, proteins, and lipid membranes, thereby inducing ROS and lipid peroxidation (183)

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Maestri et al., 2010)

However, for those who want to bypass the production step entirely, Liposomal Glutathione is often preferred due to its superior absorption