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(2017) reported that this AChE inhibitory activity is associated with FSE-mediated activation of the Akt/GSK3 pathway, which also led to ameliorated memory and learning difficulties, Al toxicity, AChE hyperactivity, amyloid (A) aggregation, and apoptosis, in rats with AD-like AlCl3induced memory loss in this study

doi: 10.1021/jm801276a 20 MukherjeeSChowdhurySChattapadhyayAPBhattacharyaA

Semax is studied in models involving neurotrophic signaling, BDNF-associated pathway research, cognitive signaling, stress-response biology, and central nervous system regulation