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These alterations not only extend its duration of action but also enable IGF-1 LR3 to circumvent binding with IGF-binding proteins, which typically impede the biological availability and efficacy of IGF-1

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[DOI] [PMC free article] [PubMed] [Google Scholar] Petrovska I

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Bone health: Certain medicines, such as glucocorticoids, may also have a negative effect on bone health

1 results in an independent cohort