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Additives like glycerol (sometimes added when freezing protein solutions) can actually protect peptides by preventing ice crystal damage and concentrating solutes during freezing

CanaveseCPetraruloMMassarentiPBeruttiSFenoglioRPaulettoDet alLong-term, low-dose, intravenous vitamin C leads to plasma calcium oxalate supersaturation in hemodialysis patients

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[DOI] [PubMed] [Google Scholar] 45.Jastreboff AM, Kaplan LM, Fras JP, Wu Q, Du Y, Gurbuz S, et al