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This explains the wide range of non-motor symptoms noticed in PD patients, including autonomic dysfunction, depression, anxiety, and cognitive impairment (42, 43)

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During the first 24 h after treatment, urine was collected every 8 h, followed by collection intervals of 24 h until sacrifice

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Of the 23 individual pharmacotherapies that have been trialled [9], none have yet provided clear and replicable signals