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Which antioxidant system shapes intracellular H 2 O 2 gradients

Furthermore, integrating redox profiling or redox signatures into personalized medicine approaches may optimize therapeutic efficacy while minimizing off-target toxicity

Magtanong L, Ko PJ, To M, Cao JY, Forcina GC, Tarangelo A et al (2019) Exogenous monounsaturated fatty acids promote a Ferroptosis-Resistant cell state

Similarly, PDE4 inhibitors (e.g., Roflumilast) reduce inflammation by modulating cyclic AMP (cAMP) signaling

85 Hyperglycemia also disrupts the CAV1CAVIN1LC3B axis, impairing autophagy and facilitating low-density lipoprotein (LDL) transcytosis, thereby accelerating atherosclerotic pathology