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Iron, in its free form, can catalyze ROS reactions (Figure 2), leading to the formation of hydroxyl radicals and lipid peroxides, to glutathione (GSH) depletion, and to the malfunction of antioxidant enzymes and cell death, called ferroptosis, which is distinct from apoptosis and necrosis [46]

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Enhanced glucose metabolism triggers mitochondrial activity by increasing AMP levels, disrupting the ATP:AMP ratio and subsequently activating AMPK

This patented technology sets it apart from other Polypodium Leucotomos extracts by ensuring a unique extraction process that maintains the optimal purity and potency of the active compounds

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In vitro experiment showed that 50% ethanolic extracts of these herbs and spices inhibit fructose-mediated protein glycation